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Advances
in Spinal Imaging
Visualizing
lesions affecting the spinal cord has always been challenging, since
many are not apparent on routine radiographs. We are frequently
presented with patients that have the complaint of ataxia, paresis
or spinal pain. Choosing which imaging tests to perform can be confusing.
Each form of imaging has its place and its own unique benefits and
pitfalls.
Plain
radiographs of the spine are useful in evaluating the vertebral
column for position of bones, continuity of the spinal column and
spinal canal, bone density, changes in the articular facet joints,
and integrity of vertebral body end plates and disc spaces. Good
positioning and radiographic technique are critical for evaluating
the spine. Many lesions may be missed completely and many anatomically
normal things can be misinterpreted as pathology, if good positioning
and technique are not applied. This is particularly true if one
is evaluating the width of the disc spaces. Sedation or general
anesthesia may be required.
Lesions
that may be readily diagnosed with plain radiographs of the spine
include spinal fractures, luxations, vertebral anomalies (such as
hemivertebrae or spina bifida), discospondylitis, and some vertebral
body tumors.
Because
the spinal cord and discs cannot be visualized, plain radiographs
are inadequate in the diagnosis of intervertebral disc extrusion,
spinal cord or nerve root tumors, or congenital spinal cord defects
(such as syringomyelia).
Myelography involves the injection of iodinated contrast into the subarachnoid
space. Radiographs performed following this injection allow visualization
of the outline of the spinal cord. Compressive lesions can be readily
seen using this technique. Disc extrusion or extradural spinal cord
tumors are commonly diagnosed with a myelogram. Vertebral instability,
such as that seen in dogs with Wobbler’s syndrome, is most readily
appreciated on myelographic views taken with the neck in several
different positions: neutral, flexed, extended, and lateral distraction.
A
myelogram does not allow us to evaluate the cauda equina for nerve
root compression, such as is seen with lumbosacral stenosis, since
the canine spinal cord ends around L5. Intramedullary spinal cord
lesions, such as neoplasia or congenital syringomyelia, may be difficult
to see or may be missed with a myelogram, since the parenchyma of
the spinal cord is not visualized.
Because
it involves injection of contrast media into the subarachnoid space,
a myelogram is an invasive procedure, and there is some risk associated
with it. General anesthesia is required. Possible complications
of myelography include transient post-myelogram seizures and worsening
of the patient’s neurologic status.
CT
(computed tomography) is basically radiography performed in an axial
plane. CT is excellent for evaluation of bone detail, and is ideal
for visualizing bone tumors, spinal fractures, and discospondylitis.
Soft tissues are better visualized than on plain radiographs, but
interpretation of subtle soft tissue lesions can still be difficult.
In the case of type I disc extrusion in chondrodystrophic breeds,
such as dachshunds, the disc material that is extruded is often
mineralized. This mineralized disc material can be easily seen on
a CT scan, and any lateralization of the disc material is also apparent.
This is not necessarily true for larger dogs or dogs with type II
disc disease, in which there is typically no mineralization of the
disc. In these patients, a myelogram in combination with a CT scan
is often needed.
Modern
CT scanners are very fast, often completing a scan in a matter of
minutes. A CT scan (without a myelogram) is non-invasive for the
patient as well. Unfortunately, it is often impossible to know whether
or not a myelogram will be needed prior to the scan.
MRI
allows the best visualization of soft tissue lesions, and is especially
useful for diagnosing intramedullary spinal cord lesions, such as
neoplasms, syringomyelia, arachnoid cysts, and even occasionally
infarcts. It is also good at diagnosis of disc disease in dogs.
MRI is non-invasive, but does require significant time to perform.
It is the most expensive imaging modality and because of the time
required, scanning of a large area (such as the thoracolumbar spine)
in a large dog can be problematic.

Photo
1: Extruded disc material at the right side of the spinal canal. A computed tomography (CT) image demonstrating extruded disc material at the right side of the spinal canal.

Photo
2: Lysis of the endplate, vertebral body, and costovertebral
junctions.
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